Amlodipine caused significant decrease in sperm motility.
Which drugs inhibit spermatogenesis?
The FDA-approved drugs that have the potential to impair human spermatogenesis
| Generic name of drug | Adverse impact on human spermatogenesis |
|---|---|
| Nitrofurantoin | Spermatogenic arrest/decreased sperm count (high doses) |
| Dapsone | Orchitis, male infertility |
| Lamotrigine | Epididymitis (rare) |
| Clomipramine hydrochloride | Epididymitis (infrequent) |
Do benzodiazepines affect sperm?
Key takeaways. The most commonly used antidepressant (SSRIs) and anti-anxiety (benzodiazepine) meds don’t have any clear, long-term impacts on eggs or sperm, though SSRIs have short-term effects on sperm. Studies on the link between these meds and pregnancy outcomes have been mixed.
Does high blood pressure affect sperm?
Existing data suggest an association between hyper- tension and impaired semen quality. Men diagnosed with hypertension have a lower semen volume, sperm motility, total sperm count, and motile sperm count relative to men in the cohort who did not carry a diagnosis of hyper- tension.
Does amlodipine affect testosterone?
Conclusion: These results suggest that long-term treatment with amlodipine might be associated with significant testicular regression and reduction in serum testosterone.
Does losartan affect sperm?
Compared to men not taking medications, men taking 1 antihypertensive medication had a statistically significant decrease in semen volume (2.0 mL vs. 2.5 mL, p=0.05) with a trend toward a lower sperm count (p=0.07). We then stratified men by individual class of antihypertensive medication [15].
What drugs increase sperm motility?
Some supplements may also help improve sperm motility. For example, one study found a 52 percent increase in sperm motility in men who took a daily supplement of 200 micrograms of selenium along with 400 units of vitamin E for at least 100 days in a row.
What medicines affect sperm quality?
Certain medications. Testosterone replacement therapy, long-term anabolic steroid use, cancer medications (chemotherapy), certain antifungal and antibiotic medications, some ulcer medications, and other medications can impair sperm production and decrease male fertility.
Can a man with low sperm pregnant a woman?
Having a low sperm count decreases the odds that one of your sperm will fertilize your partner’s egg, resulting in pregnancy. Nonetheless, many men who have a low sperm count are still able to father a child.
