It works by destroying the tissue of the growth. A few hours after podophyllum is applied to a wart, the wart becomes blanched (loses all color). In 24 to 48 hours, the medicine causes death of the tissue. After about 72 hours, the wart begins to slough or come off and gradually disappears.
How long should Podophyllin be applied?
Adults and children—Apply to the affected area(s) of the skin and leave on the skin for one to six hours. Treatment may be repeated every week for up to six weeks.
How do you use Podophyllin for warts?
Apply directly to the wart and not the skin around it. You can apply petroleum jelly (Vaseline) to the skin around the wart to keep the medicine from getting onto healthy skin. Allow the treated wart to dry completely before dressing. Do not apply this medicine to a mole or birthmark.
Can Podophyllin treat warts?
Medical Treatment. Cytotoxic podophyllin is the most common topical agent used to treat warts. It is a resin extract from the root of the May apple plant.
Can Vaseline cure warts?
However, it has been shown that salicylic acid is effective at treating warts. Salicylic acid and other wart treatments also destroy healthy skin, so it is important to protect your skin before applying the treatment. You can use petroleum jelly or a corn plaster to cover the skin around the wart.
What is the side effect of podophyllin?
The use of topical podophyllin has been known to result in paresthesia, polyneuritis, paralytic ileus, pyrexia, leukopenia, thrombocytopenia, coma and death(5).
Is podophyllin an antibiotic?
Podophyllin, a resin derived from the May apple (Podophyllum peltatum Linné), contains the active agent podophyllotoxin, which is a cytotoxic agent that arrests mitosis in metaphase. It is a physician-applied medicine used in the treatment of external genital warts and condyloma acuminatum.
What are the side effect of podophyllin?
When taken by mouth: Podophyllum is poisonous and is LIKELY UNSAFE when taken by mouth. It may cause nausea, vomiting, dizziness, headache, spasms, fever, visual changes and hallucinations, low blood pressure, bone marrow problems, paralysis, coma, liver problems, kidney problems, and death.
What is the work of Podophyllin cream?
Is Podophyllin cream painful?
Common side effects may include: swelling, redness, or tenderness of treated skin; itching; or. burning pain.
How do I get rid of a wart on my thigh?
To treat a wart, soak it for 10 to 15 minutes (you can do this in the shower or bath), file away the dead warty skin with an emery board or pumice stone, and apply the salicylic acid. Do this once or twice a day for 12 weeks.
What cream removes warts?
Nonprescription wart removal products such as salicylic acid are available as a patch, ointment, pad and liquid. For common warts, look for a 17 percent salicylic acid solution. These products (Compound W, Dr. Scholl’s Clear Away Wart Remover, others) are usually used daily, often for a few weeks.
How do I apply podocon-25® (podophyllin)?
Use supplied applicator to apply Podocon-25® (podophyllin) sparingly to lesion. Avoid contact with healthy tissue. Allow to dry thoroughly. Only intact (no bleeding) lesions should be treated.
What is podophyllin used for in medical terms?
CLINICAL PHARMACOLOGY. Podophyllin is a cytotoxic agent that has been used topically in the treatment of genital warts. It arrests mitosis in metaphase, an effect it shares with other cytotoxic agents such as the vinca alkaloids(2).
How do you apply podophyllum resin?
Use a toothpick or a cotton-tipped or glass applicator to apply podophyllum resin. Apply 1 drop at a time, allowing time for drying between drops, until the affected area is covered.
What are the side effects of topical podophyllin?
The use of topical podophyllin has been known to result in paresthesia, polyneuritis, paralytic ileus, pyrexia, leukopenia, thrombocytopenia, coma and death (5). No information provided. 5) Fisher: Severe Systemic and Local Reactions to Topical Podophyllum Resins; Cutis, Volume 28, 1981. Podophyllin is a powerful caustic and severe irritant.
