Any drug that reduces the normal rate of secretion of a body fluid, usually one that reduces acid secretion into the stomach. Such drugs include antimuscarinic drugs, H2-receptor antagonists (see antihistamine), and proton-pump inhibitors.
Which drug is Antisecretory agent?
Although proton pump inhibitors are the most widely used antisecretory agents, H2 receptor antagonists also enhance antibiotic effects.
What are antisecretory drugs used for?
Antisecretory compounds are used for the long-term treatment of GERD, a chronic disorder of the esophagus that results a decrease of the low esophageal sphincter (LES) barrier tone, leading to acid reflux, epithelial erosion, ulceration, and, sometimes, hyperplasia accompanied by inflammation.
What bacteria causes secretory diarrhea?
Secretory diarrhea occurs when your body secretes electrolytes into your intestine. This causes water to build up. It can be caused a number of factors, including: bacterial infection such as salmonella and E.
What drugs are PPI?
Types of PPIs
- Omeprazole (Prilosec), also available over-the-counter (without a prescription)
- Esomeprazole (Nexium), also available over-the-counter (without a prescription)
- Lansoprazole (Prevacid), also available over-the-counter (without a prescription)
- Rabeprazole (AcipHex)
- Pantoprazole (Protonix)
Which of the following listed drug is a proton pump inhibitor?
The currently available PPIs include: omeprazole (Prilosec, Prilosec OTC, Zegerid) lansoprazole (Prevacid) pantoprazole (Protonix)
What are examples of H2 blockers?
Types of H2 Blockers
- Famotidine (Pepcid AC, Pepcid Oral, Zantac 360)
- Cimetidine (Tagamet, Tagamet HB)
- Nizatidine Capsules (Axid AR, Axid Capsules, Nizatidine Capsules)
What is PPI in pharmacy?
Proton pump inhibitors (PPIs) are medicines that work by reducing the amount of stomach acid made by glands in the lining of your stomach.
What is motility Diarrhoea?
Disease Ontology : 12 Motility-related diarrhea is a diarrhea which is caused by the rapid movement of food through the intestines (hypermotility). If the food moves too quickly through the GI tract, there is not enough time for sufficient nutrients and water to be absorbed.
Which antisecretory agents are effective in the treatment of diarrhea?
In persons from resource-poor countries, antisecretory agents (e.g., racecadotril) seem to be as effective at improving symptoms of diarrhea as antimotility agents (e.g., loperamide), but with fewer adverse effects.
Is oral rehydration therapy effective in the treatment of watery diarrhea?
Although oral rehydration therapy has reduced mortality during the past 30 years ago, the search for agents that will directly inhibit intestinal secretory mechanisms and thereby reduce faecal losses in patients with high-volume watery diarrhea has continued for more than 20 years.
What are the potential targets for antisecretory agents?
A variety of potential targets for antisecretory agents have been explored which include loci within the enterocyte (the chloride channel, calcium-calmodulin) and other sites such as enteric nerves and endogenous mediators (such as 5-HT, prostaglandins).
What is the role of enkephalin in the pathogenesis of diarrhea?
Recent work has highlighted the importance of neurohumoral mechanisms in the pathogenesis of acute diarrhea. Potentiation of the effects of endogenous enkephalin activity by enkephalinase inhibition has already produced a safe, effective anti-secretory drug, racecadotril.
