Enterovirus 71 (EV71) neurological disease is a rare but serious complication of infection with enterovirus 71, a virus which most commonly causes the mild childhood illness hand, foot and mouth disease. Cases and outbreaks of enterovirus 71 neurological disease are rare.
Is there a vaccine for enterovirus 71?
On December 3rd 2015, the China Food and Drug Administration (CFDA) approved the first inactivated Enterovirus 71 (EV71) whole virus vaccine for preventing severe hand, foot and mouth disease (HFMD).
Is there a vaccine for enterovirus?
Prevention & Treatment There is no vaccine to protect you from non-polio enterovirus infection.
What is associated with enterovirus 71?
Enterovirus 71 Encephalomyelitis Enterovirus 71 (EV71) has been associated with hand, foot, and mouth disease; herpangina; aseptic meningitis; and poliomyelitis-like flaccid paralysis. More recently EV71 has been associated with unusual cases of fulminant encephalitis, pulmonary edema and hemorrhage, and heart failure.
How bad is enterovirus?
Complications from enteroviruses are not common. But they can cause severe problems such as: Inflammation of the brain (encephalitis) Inflammation of the tissues around the brain and spinal cord (meningitis)
What is coxsackievirus A16 and Enterovirus 71?
Hand, foot, and mouth disease (HFMD) is an acute viral disease caused by human enteroviruses, especially human enterovirus 71 (HEV71) and coxsackievirus A16 (CVA16), and mainly affects infants and young children.
Where does enterovirus 71 come from?
The picornaviruses belong to the Picornaviridae, a family of small non-enveloped viruses with a single-stranded positive-sense RNA genome of about 7500 nucleotides. EV71 was first isolated from the faeces of a female suffering from encephalitis in 1969 in California.
What is Herpangina caused by?
Herpangina is an acute viral illness in children. Common symptoms are small blisterlike bumps or sores (ulcers) in the mouth and fever. It is caused by a virus. The most common cause is coxsackievirus A16.
What kills enterovirus?
Common disinfectants and detergents will kill enteroviruses, Morse says, so clean frequently touched surfaces like doorknobs and toys according to manufacturers’ directions.
What is the most serious disease caused by EV71?
Children <4 years of age are particularly susceptible to the most severe forms of EV71-associated neurological disease, including meningitis, brain-stem and/or cerebellar encephalitis, and poliomyelitis-like paralysis. The neurological complications of EV71 infection may occasionally cause permanent paralysis or death.
Is enterovirus a respiratory virus?
Enterovirus D68 (EV-D68) causes a respiratory illness, primarily in children; symptoms usually resemble those of a cold (eg, rhinorrhea, cough, malaise, fever in a few children). Some children, particularly those with asthma.
How long can enterovirus last?
The majority of enterovirus infections last about a week to 10 days and have no complications.
