An estimated GFR (eGFR) calculated from serum creatinine using an isotope dilution mass spectrometry (IDMS) traceable equation is a simple and effective way in which laboratories can help health care providers detect CKD among those with risk factors—diabetes, hypertension, cardiovascular disease, or family history of …
What is the normal range for GFR?
A GFR of 60 or higher is in the normal range. A GFR below 60 may mean kidney disease. A GFR of 15 or lower may mean kidney failure.
What is the normal creatinine level?
The typical range for serum creatinine is: For adult men, 0.74 to 1.35 mg/dL (65.4 to 119.3 micromoles/L) For adult women, 0.59 to 1.04 mg/dL (52.2 to 91.9 micromoles/L)
What does mL/min 1.73m2 mean?
Your eGFR is reported in millilitres per minute which is written as mL/min/1.73m2 (the “1.73m2” indicates a result expressed relative to body surface area). A normal GFR in a young adult is greater than 90 mL/min/1.73m2.
What is ACR measurement?
Albumin-to-creatinine ratio (ACR) is the first method of preference to detect elevated protein. The recommended method to evaluate albuminuria is to measure urinary ACR in a spot urine sample. ACR is calculated by dividing albumin concentration in milligrams by creatinine concentration in grams.
What is eGFR if African am?
eGFR stands for estimated glomerular filtration rate. This estimate of kidney function can help doctors diagnose and treat kidney disease. The formulas currently used for eGFR modify results based on whether or not you are Black.
What does 90ml min 1.73m2 mean?
• A result of 60–89 mL/min/1.73 m2 for three. months or more, along with kidney damage. (such as persistent protein in the urine), means the person has early kidney disease. • When GFR is <60 for three months or more, chronic kidney disease (CKD) is present.
What does traceable to IDMS mean?
What does “Traceable to IDMS” mean? all laboratories should now be using a creatinine method that has been standardized or traceable to isotope dilution mass spectrometry (IDMS). The way creatinine levels are calibrated affects the GFR estimating equation slightly.
What is the IDMS-traceable MDRD Study equation?
The following is the IDMS-traceable MDRD Study equation (for creatinine methods calibrated to an IDMS reference method) GFR (mL/min/1.73 m 2) = 175 × (S cr) -1.154 × (Age) -0.203 × (0.742 if female) × (1.212 if African American)
Why should I use an IDMS traceable equation when estimating GFR?
Because creatinine results that are calibrated to IDMS may differ by 5 to 30% compared to uncalibrated results, 1 use of a non-IDMS traceable equation with IDMS calibrated results will yield an inaccurate eGFR. Therefore, all laboratories should use an IDMS traceable equation when estimating and reporting GFR.
What does IDMS stand for?
The Infrastructure Delivery Management System (IDMS) is a government management system for planning, budgeting, procurement, delivery, maintenance, operation, monitoring and evaluation of infrastructure.
